1wae

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[[Image:1wae.gif|left|200px]]
[[Image:1wae.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1wae |SIZE=350|CAPTION= <scene name='initialview01'>1wae</scene>, resolution 1.95&Aring;
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The line below this paragraph, containing "STRUCTURE_1wae", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Chain+A'>AC1</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrite_reductase_(NO-forming) Nitrite reductase (NO-forming)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.2.1 1.7.2.1] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1wae| PDB=1wae | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wae OCA], [http://www.ebi.ac.uk/pdbsum/1wae PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1wae RCSB]</span>
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}}
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'''CRYSTAL STRUCTURE OF H129V MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE'''
'''CRYSTAL STRUCTURE OF H129V MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE'''
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Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15554622 15554622]
Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15554622 15554622]
[[Category: Achromobacter xylosoxidans]]
[[Category: Achromobacter xylosoxidans]]
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[[Category: Nitrite reductase (NO-forming)]]
 
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Antonyuk, S V.]]
[[Category: Antonyuk, S V.]]
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[[Category: Sawers, G.]]
[[Category: Sawers, G.]]
[[Category: Strange, R W.]]
[[Category: Strange, R W.]]
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[[Category: copper protein]]
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[[Category: Copper protein]]
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[[Category: nitrite reductase]]
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[[Category: Nitrite reductase]]
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[[Category: reductase]]
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[[Category: Reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:23:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:33:32 2008''
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Revision as of 10:23, 3 May 2008

Image:1wae.gif

Template:STRUCTURE 1wae

CRYSTAL STRUCTURE OF H129V MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE


Overview

Copper nitrite reductases contain both an electron-transfer type 1 Cu site and a catalytic type 2 Cu site. We have mutated one of the type 2 copper ligating histidines to observe the effect on catalytic turnover. This mutation has created a unique site where Cu is ligated by 2 His Nepsilon2 atoms alone.

About this Structure

1WAE is a Single protein structure of sequence from Achromobacter xylosoxidans. Full crystallographic information is available from OCA.

Reference

Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:15554622 Page seeded by OCA on Sat May 3 13:23:03 2008

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