1wav

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[[Image:1wav.gif|left|200px]]
[[Image:1wav.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1wav |SIZE=350|CAPTION= <scene name='initialview01'>1wav</scene>, resolution 2.5&Aring;
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The line below this paragraph, containing "STRUCTURE_1wav", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=IPH:PHENOL'>IPH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1wav| PDB=1wav | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wav OCA], [http://www.ebi.ac.uk/pdbsum/1wav PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1wav RCSB]</span>
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}}
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'''CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN'''
'''CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN'''
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[[Category: Liang, D C.]]
[[Category: Liang, D C.]]
[[Category: Wan, Z L.]]
[[Category: Wan, Z L.]]
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[[Category: hormone]]
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[[Category: Hormone]]
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[[Category: insulin]]
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[[Category: Insulin]]
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[[Category: phenol]]
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[[Category: Phenol]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:23:56 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:33:39 2008''
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Revision as of 10:23, 3 May 2008

Image:1wav.gif

Template:STRUCTURE 1wav

CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN


Overview

The form-B monoclinic insulin crystal was obtained from the sodium citrate buffer with 1% zinc chloride, keeping phenolic content between 0.76% and 1.25%. Its space group is P2(1), cell constants are: a = 4.924 nm, b = 6.094 nm, c = 4.818 nm, beta = 95.8 degrees. There are 6 insulin molecules which form a hexamer. The initial phase was obtained by using rotation function program of X-PLOR program package and molecular packing program of our laboratory. The molecular model was chosen from 4 zinc bovine insulin hexamer. After the preliminary refinement by using the macromolecular rigid body refinement technique, the molecular model was further refined and adjusted by using the energy-minimizing stereochemically restrained least-squared refinement on the difference Fourier maps. The final R-factor is 22.4% at 0.3 nm resolution, the r.m.s. deviations from standard bond length and bond angle are 0.0022 nm and 4.7 degrees, respectively.

About this Structure

1WAV is a Protein complex structure of sequences from Sus scrofa. Full crystallographic information is available from OCA.

Reference

Molecular replacement study on form-B monoclinic crystal of insulin., Ding J, Wan Z, Chang W, Liang D, Sci China C Life Sci. 1996 Apr;39(2):144-53. PMID:8760462 Page seeded by OCA on Sat May 3 13:23:56 2008

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