9g4t

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m (Protected "9g4t" [edit=sysop:move=sysop])
Current revision (05:35, 30 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9g4t is ON HOLD until Paper Publication
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==Beta carbonic anhydrase CsoSCA from the Halothiobacillus neapolitanus alpha-carboxysome==
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<StructureSection load='9g4t' size='340' side='right'caption='[[9g4t]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
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Authors: Ng, P.C., Marles-Wright, J., Basle, A., Liu, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9g4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus] and [https://en.wikipedia.org/wiki/Streptococcus_sp._'group_G' Streptococcus sp. 'group G']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9G4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9G4T FirstGlance]. <br>
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Description: Beta carbonic anhydrase CsoSCA from the Halothiobacillus neapolitanus alpha-carboxysome
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.51&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Ng, P.C]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9g4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9g4t OCA], [https://pdbe.org/9g4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9g4t RCSB], [https://www.ebi.ac.uk/pdbsum/9g4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9g4t ProSAT]</span></td></tr>
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[[Category: Marles-Wright, J]]
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</table>
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[[Category: Liu, L]]
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== Function ==
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[[Category: Basle, A]]
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[https://www.uniprot.org/uniprot/SPG1_STRSG SPG1_STRSG] Binds to the constant Fc region of IgG with high affinity.[https://www.uniprot.org/uniprot/CSOCA_HALNC CSOCA_HALNC] Reversible hydration of carbon dioxide (PubMed:14729686, PubMed:17012396, PubMed:18258595). Essential for chemolithotrophic carbon dioxide fixation, supplies CO(2) to RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) in the carboxysome (Probable) (PubMed:18258595). There are estimated to be 40 CsoSCA dimers per carboxysome (Ref.5).<ref>PMID:14729686</ref> <ref>PMID:17012396</ref> <ref>PMID:18258595</ref> <ref>PMID:18258595</ref> <ref>PMID:14729686</ref> Unlike beta-carboxysomes, alpha-carboxysomes (Cb) can form without cargo protein. CsoS2 is essential for Cb formation and is also capable of targeting foreign proteins to the Cb. The Cb shell assembles with the aid of CsoS2; CsoS1A, CsoS1B and CsoS1C form the majority of the shell while CsoS4A and CsoS4B form vertices. CsoS1D forms pseudohexamers that probably control metabolite flux into and out of the shell.<ref>PMID:33116131</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Halothiobacillus neapolitanus]]
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[[Category: Large Structures]]
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[[Category: Streptococcus sp. 'group G']]
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[[Category: Basle A]]
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[[Category: Liu L]]
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[[Category: Marles-Wright J]]
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[[Category: Ng PC]]

Current revision

Beta carbonic anhydrase CsoSCA from the Halothiobacillus neapolitanus alpha-carboxysome

PDB ID 9g4t

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