9g6i
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of S. epidermidis ClpP in complex with bortezomib - cocrystallization== | |
| - | + | <StructureSection load='9g6i' size='340' side='right'caption='[[9g6i]], [[Resolution|resolution]] 1.74Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9g6i]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_epidermidis Staphylococcus epidermidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9G6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9G6I FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BO2:N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE'>BO2</scene></td></tr> |
| - | [[Category: Alves Franca | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9g6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9g6i OCA], [https://pdbe.org/9g6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9g6i RCSB], [https://www.ebi.ac.uk/pdbsum/9g6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9g6i ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [https://www.uniprot.org/uniprot/A0A0N1MQL5_STAEP A0A0N1MQL5_STAEP] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.[HAMAP-Rule:MF_00444][RuleBase:RU000550] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus epidermidis]] | ||
| + | [[Category: Alves Franca B]] | ||
| + | [[Category: Betzel C]] | ||
| + | [[Category: Rohde H]] | ||
Current revision
Crystal structure of S. epidermidis ClpP in complex with bortezomib - cocrystallization
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