9li2
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==DCA-bound state of hPAC structure== | |
| - | + | <StructureSection load='9li2' size='340' side='right'caption='[[9li2]], [[Resolution|resolution]] 3.72Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9li2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LI2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LI2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.72Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXC:(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC+ACID'>DXC</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9li2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9li2 OCA], [https://pdbe.org/9li2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9li2 RCSB], [https://www.ebi.ac.uk/pdbsum/9li2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9li2 ProSAT]</span></td></tr> |
| - | [[Category: Chen | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PACC1_HUMAN PACC1_HUMAN] Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH (PubMed:31023925, PubMed:31318332). Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling (PubMed:31023925, PubMed:31318332).<ref>PMID:31023925</ref> <ref>PMID:31318332</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen X]] | ||
| + | [[Category: Zhang H]] | ||
Current revision
DCA-bound state of hPAC structure
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