GTPase Hras 3D structures

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Current revision (09:47, 3 August 2025) (edit) (undo)
 
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*HRAS p21 catalytic domain residues 1-166
*HRAS p21 catalytic domain residues 1-166
-
**[[5p21]], [[221p]], [[1ioz]], [[1p2t]], [[3k8y]], [[3l8z]], [[3rry]], [[3tgp]], [[3lbh]], [[4dlr]], [[4dls]], [[4dlt]], [[4dlu]], [[4dlv]], [[4dlw]], [[4dlx]], [[4dly]], [[4dlz]] - hHRAS – human<BR / >
+
**[[1ioz]], [[1p2t]], [[221p]], [[3k8y]], [[3l8z]], [[3lbh]], [[3rry]], [[3tgp]], [[4dlr]], [[4dls]], [[4dlt]], [[4dlu]], [[4dlv]], [[4dlw]], [[4dlx]], [[4dly]], [[4dlz]], [[5p21]], [[7og9]], [[8bwg]] - hHRAS – human<BR / >
**[[1plj]], [[1plk]], [[1pll]] – hHRAS - Laue<BR / >
**[[1plj]], [[1plk]], [[1pll]] – hHRAS - Laue<BR / >
-
**[[221p]], [[421p]], [[521p]], [[621p]], [[721p]], [[821p]], [[1agp]], [[3i3s]], [[3k9n]], [[3lo5]], [[3k9l]], [[3oiu]], [[3oiv]], [[3oiw]] – hHRAS (mutant)<br />
+
**[[1agp]], [[221p]], [[3i3s]], [[3k9n]], [[3lo5]], [[3k9l]], [[3oiu]], [[3oiv]], [[3oiw]], [[421p]], [[521p]], [[621p]], [[721p]], [[821p]], [[8elk]], [[8elr]], [[8els]], [[8elt]], [[8elu]], [[8elv]], [[8elw]], [[8elx]], [[8ely]], [[8elz]], [[8em0]], [[8fg3]], [[8fg4]] – hHRAS (mutant)<br />
**[[2n42]], [[2n46]] - hHRAS (mutant) – NMR<br />
**[[2n42]], [[2n46]] - hHRAS (mutant) – NMR<br />
**[[3v4f]] – HRAS - rat
**[[3v4f]] – HRAS - rat
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*HRAS p21 catalytic domain complex with nucleotides
*HRAS p21 catalytic domain complex with nucleotides
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**[[1q21]], [[4q21]] – hHRAS + GDP<BR / >
+
**[[1q21]], [[4q21]], [[8cnj]], [[8cnn]] – hHRAS + GDP<BR / >
-
**[[1crp]], [[1crq]], [[1crr]], [[1aa9]] – hHRAS + GDP - NMR<BR / >
+
**[[1aa9]], [[1crp]], [[1crq]], [[1crr]] – hHRAS + GDP - NMR<BR / >
-
**[[4l9s]], [[6dzh]], [[6mqt]], [[1lf0]], [[1zw6]], [[2cl6]], [[2cl7]], [[2clc]], [[2cld]], [[2ce2]], [[2quz]], [[2x1v]], [[2q21]], [[7jii]], [[7tam]] [[2evw]], [[1jah]], [[1jai]] - hHRAS (mutant) + GDP<br />
+
**[[1lf0]], [[1zw6]], [[2cl6]], [[2cl7]], [[2clc]], [[2cld]], [[2ce2]], [[2evw]], [[2q21]], [[2quz]], [[2x1v]], [[4l9s]], [[6dzh]], [[6mqt]], [[7jii]], [[7tam]] - hHRAS (mutant) + GDP<br />
**[[5vbe]], [[5vbz]] - hHRAS (mutant) + GDP + pyrazole derivative<br />
**[[5vbe]], [[5vbz]] - hHRAS (mutant) + GDP + pyrazole derivative<br />
-
**[[7oga]], [[7ogb]], [[7ogc]] - hHRAS + GNP <br />
+
**[[7oga]], [[7ogb]], [[7ogc]], [[8osm]], [[8osn]], [[8oso]] - hHRAS + GNP <br />
**[[7jif]], [[7jig]], [[7jih]], [[7ogd]], [[7oge]], [[7ogf]] - hHRAS (mutant) + GNP <br />
**[[7jif]], [[7jig]], [[7jih]], [[7ogd]], [[7oge]], [[7ogf]] - hHRAS (mutant) + GNP <br />
**[[5zc6]] - hHRAS (mutant) + GNP + naphthalene derivative<br />
**[[5zc6]] - hHRAS (mutant) + GNP + naphthalene derivative<br />
**[[5wdo]] - hHRAS + GMPPNP<br />
**[[5wdo]] - hHRAS + GMPPNP<br />
**[[4l9w]], [[5wdp]], [[5wdq]] - hHRAS (mutant) + GMPPNP<br />
**[[4l9w]], [[5wdp]], [[5wdq]] - hHRAS (mutant) + GMPPNP<br />
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**[[6q21]], [[121p]] – hHRAS + GCP<BR / >
+
**[[121p]], [[6q21]] – hHRAS + GCP<BR / >
**[[1qra]] - hHRAS + GTP<BR / >
**[[1qra]] - hHRAS + GTP<BR / >
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**[[1lf0]], [[1zw6]], [[2cl6]], [[2cl7]], [[2clc]], [[2evw]], [[1jah]], [[1jai]]- hHRAS (mutant) + GTP<BR / >
+
**[[1jah]], [[1jai]], [[1lf0]], [[1zw6]], [[2cl6]], [[2cl7]], [[2clc]], [[2evw]] - hHRAS (mutant) + GTP<BR / >
-
**[[1clu]], [[1rvd]], [[1iaq]], [[1gnr]] - hHRAS (mutant) + GTP derivative<br / >
+
**[[1clu]], [[1gnr]], [[1iaq]], [[1rvd]] - hHRAS (mutant) + GTP derivative<br / >
**[[1ctq]], [[4efl]], [[4rsg]], [[5b2z]], [[5b30]], [[5x9s]] - hHRAS + GPPNHP<BR / >
**[[1ctq]], [[4efl]], [[4rsg]], [[5b2z]], [[5b30]], [[5x9s]] - hHRAS + GPPNHP<BR / >
**[[1xcm]], [[2cl0]], [[2rga]], [[2rgb]], [[2rgc]], [[2rgd]], [[2rge]], [[2rgg]], [[3kkm]], [[3kkn]], [[4efm]], [[4efn]], [[6e6c]], [[6e6p]], [[7dph]], [[7dpj]] - hHRAS (mutant) + GPPNHP<BR / >
**[[1xcm]], [[2cl0]], [[2rga]], [[2rgb]], [[2rgc]], [[2rgd]], [[2rge]], [[2rgg]], [[3kkm]], [[3kkn]], [[4efm]], [[4efn]], [[6e6c]], [[6e6p]], [[7dph]], [[7dpj]] - hHRAS (mutant) + GPPNHP<BR / >
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**[[3lbh]], [[3lbi]], [[3lbn]] - hHRAS + salt + guanylate derivative<br / >
**[[3lbh]], [[3lbi]], [[3lbn]] - hHRAS + salt + guanylate derivative<br / >
**[[3l8y]] - hHRAS + cyclen + guanylate derivative<br / >
**[[3l8y]] - hHRAS + cyclen + guanylate derivative<br / >
-
**[[6zl3]] – hHRAS + inhibitor + GDP<br />
+
**[[6zl3]], [[8tlr]] – hHRAS + inhibitor + GDP<br />
**[[6zj0]] – hHRAS + inhibitor + GCP<br />
**[[6zj0]] – hHRAS + inhibitor + GCP<br />
**[[2lwi]] – hHRAS (mutant) + inhibitor + GNP<br />
**[[2lwi]] – hHRAS (mutant) + inhibitor + GNP<br />
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*HRAS p21 catalytic domain complex with protein
*HRAS p21 catalytic domain complex with protein
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**[[1wq1]] - hHRAS + p120GAP catalytic domain<BR / >
+
**[[1wq1]], [[8bos]] - hHRAS + p120GAP catalytic domain<BR / >
**[[1bkd]], [[1nvw]] - hHRAS + son of sevenless-1<BR / >
**[[1bkd]], [[1nvw]] - hHRAS + son of sevenless-1<BR / >
**[[5wfo]], [[5wfp]], [[5wfq]], [[5wfr]] - hHRAS + son of sevenless-1 homolog<br />
**[[5wfo]], [[5wfp]], [[5wfq]], [[5wfr]] - hHRAS + son of sevenless-1 homolog<br />
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**[[1nvu]], [[1nvv]], [[1nvx]], [[1xd2]], [[4nyi]], [[4nyj]], [[4nym]] - hHRAS (mutant) + son of sevenless-1 homolog<BR / >
+
**[[1nvu]], [[1nvv]], [[1nvx]], [[1xd2]], [[4nyi]], [[4nyj]], [[4nym]], [[6v94]], [[6v9f]], [[6v9j]], [[6v9l]], [[6v9m]], [[6v9n]], [[6v9o]] - hHRAS (mutant) + son of sevenless-1 homolog<BR / >
**[[4uru]], [[4urv]], [[4urw]], [[4urx]], [[4ury]], [[4urz]], [[4us0]], [[4us1]], [[4us2]] - hHRAS + son of sevenless-1 + inhibitor<br />
**[[4uru]], [[4urv]], [[4urw]], [[4urx]], [[4ury]], [[4urz]], [[4us0]], [[4us1]], [[4us2]] - hHRAS + son of sevenless-1 + inhibitor<br />
**[[6bvj]], [[6bvk]] - hHRAS + son of sevenless-1 + activator<br />
**[[6bvj]], [[6bvk]] - hHRAS + son of sevenless-1 + activator<br />
 +
**[[8be6]], [[8be7]], [[8be8]], [[8be9]], [[8bea]] - hHRAS + son of sevenless-1 + peptide<br />
**[[6bvi]], [[6bvl]], [[6bvm]], [[6cuo]], [[6cup]], [[6cur]], [[6d55]], [[6d56]], [[6d59]], [[6d5e]], [[6d5g]], [[6d5h]], [[6d5j]], [[6d5l]], [[6d5m]], [[6d5v]], [[6d5w]] - hHRAS (mutant) + son of sevenless-1 + activator<br />
**[[6bvi]], [[6bvl]], [[6bvm]], [[6cuo]], [[6cup]], [[6cur]], [[6d55]], [[6d56]], [[6d59]], [[6d5e]], [[6d5g]], [[6d5h]], [[6d5j]], [[6d5l]], [[6d5m]], [[6d5v]], [[6d5w]] - hHRAS (mutant) + son of sevenless-1 + activator<br />
**[[1k8r]] - hHRAS + Byr2 RAS-binding domain<BR / >
**[[1k8r]] - hHRAS + Byr2 RAS-binding domain<BR / >
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**[[3kud]] - hHRAS + RAF proto-oncogene Ser/Thr-protein kinase + GDP<br />
**[[3kud]] - hHRAS + RAF proto-oncogene Ser/Thr-protein kinase + GDP<br />
**[[4g0n]], [[7jhp]] - hHRAS + RAF proto-oncogene Ser/Thr-protein kinase + GNP<br />
**[[4g0n]], [[7jhp]] - hHRAS + RAF proto-oncogene Ser/Thr-protein kinase + GNP<br />
-
**[[6ntc]], [[4g3x]], [[6ntd]] - hHRAS (mutant) + RAF proto-oncogene Ser/Thr-protein kinase + GNP<br />
+
**[[4g3x]], [[6ntc]], [[6ntd]] - hHRAS (mutant) + RAF proto-oncogene Ser/Thr-protein kinase + GNP<br />
**[[1lfd]] - hHRAS + Ral guanine nucleotide dissociation stimulator RAS-binding domain<br />
**[[1lfd]] - hHRAS + Ral guanine nucleotide dissociation stimulator RAS-binding domain<br />
**[[4k81]] – hHRAS + growth factor receptor-bound protein<br />
**[[4k81]] – hHRAS + growth factor receptor-bound protein<br />
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**[[1he8]] – hHRAS (mutant) + P3K<br />
**[[1he8]] – hHRAS (mutant) + P3K<br />
**[[6kyh]] – hHRAS + Shank3 + GNP<br />
**[[6kyh]] – hHRAS + Shank3 + GNP<br />
 +
**[[8tbg]] – hHRAS + PPIASE + inhibitor<br />
**[[7vv8]], [[7vv9]], [[7vvg]] – hHRAS + TORC2 + GNP<br />
**[[7vv8]], [[7vv9]], [[7vvg]] – hHRAS + TORC2 + GNP<br />
**[[7l0f]], [[7l0g]] – hHRAS + monobody + GSP<br />
**[[7l0f]], [[7l0g]] – hHRAS + monobody + GSP<br />

Current revision

3D structures of GTPase Hras

Updated on 03-August-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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