9geq
From Proteopedia
(Difference between revisions)
m (Protected "9geq" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Native dimeric Myeloperoxidase bound to nucleosome core particle; composite map== | |
| - | + | <StructureSection load='9geq' size='340' side='right'caption='[[9geq]], [[Resolution|resolution]] 3.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9geq]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GEQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.12Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9geq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9geq OCA], [https://pdbe.org/9geq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9geq RCSB], [https://www.ebi.ac.uk/pdbsum/9geq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9geq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Burn GL]] | ||
| + | [[Category: Prumbaum D]] | ||
| + | [[Category: Raisch T]] | ||
| + | [[Category: Raunser S]] | ||
| + | [[Category: Tacke S]] | ||
| + | [[Category: Thee S]] | ||
| + | [[Category: Winkler M]] | ||
| + | [[Category: Zychlinsky A]] | ||
Current revision
Native dimeric Myeloperoxidase bound to nucleosome core particle; composite map
| |||||||||||
Categories: Homo sapiens | Large Structures | Synthetic construct | Xenopus laevis | Burn GL | Prumbaum D | Raisch T | Raunser S | Tacke S | Thee S | Winkler M | Zychlinsky A
