9jtn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:44, 6 August 2025) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 9jtn is ON HOLD until Paper Publication
+
==Human glucose 6 phosphate catalytic subunit 1 (hG6PC1) bound with phosphate.==
-
 
+
<StructureSection load='9jtn' size='340' side='right'caption='[[9jtn]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-
Authors: Chen, Q., Zhao, Y., Wang, Y.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[9jtn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JTN FirstGlance]. <br>
-
Description: Human glucose 6 phosphate catalytic subunit 1 (hG6PC1) bound with phosphate.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P5S:O-[(R)-{[(2R)-2,3-BIS(OCTADECANOYLOXY)PROPYL]OXY}(HYDROXY)PHOSPHORYL]-L-SERINE'>P5S</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
[[Category: Chen, Q]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jtn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jtn OCA], [https://pdbe.org/9jtn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jtn RCSB], [https://www.ebi.ac.uk/pdbsum/9jtn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jtn ProSAT]</span></td></tr>
-
[[Category: Zhao, Y]]
+
</table>
-
[[Category: Wang, Y]]
+
== Disease ==
 +
[https://www.uniprot.org/uniprot/G6PC1_HUMAN G6PC1_HUMAN] Glycogen storage disease due to glucose-6-phosphatase deficiency type Ia. The disease is caused by variants affecting the gene represented in this entry.
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/G6PC1_HUMAN G6PC1_HUMAN] Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.<ref>PMID:10960498</ref> <ref>PMID:12093795</ref> <ref>PMID:15542400</ref> <ref>PMID:9332655</ref> <ref>PMID:9497333</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Chen Q]]
 +
[[Category: Wang Y]]
 +
[[Category: Zhao Y]]

Current revision

Human glucose 6 phosphate catalytic subunit 1 (hG6PC1) bound with phosphate.

PDB ID 9jtn

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/9jtn"
Personal tools