1zoq

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(New page: 200px<br /> <applet load="1zoq" size="450" color="white" frame="true" align="right" spinBox="true" caption="1zoq, resolution 2.37&Aring;" /> '''IRF3-CBP complex'''...)
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Revision as of 18:31, 12 November 2007

Image:1zoq.gif

1zoq, resolution 2.37Å

Drag the structure with the mouse to rotate

IRF3-CBP complex

Contents

Overview

Interferon regulatory factor (IRF) 3 plays a critical role in triggering, the activation of interferon antiviral genes. The structure of IRF-3 in, association with the CBP/p300 coactivator by in this issue of Structure, illuminates the mechanism of IRF activation and the structural, flexibilities inherent in CBP/p300.

Disease

Known diseases associated with this structure: Blue-cone monochromacy OMIM:[303900], Colorblindness, protan OMIM:[303900], Rubenstein-Taybi syndrome OMIM:[600140]

About this Structure

1ZOQ is a Protein complex structure of sequences from Homo sapiens. Active as Histone acetyltransferase, with EC number 2.3.1.48 Full crystallographic information is available from OCA.

Reference

IRF-3 releases its inhibitions., Hiscott J, Lin R, Structure. 2005 Sep;13(9):1235-6. PMID:16154077

Page seeded by OCA on Mon Nov 12 20:38:02 2007

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