9pn0

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Current revision (06:23, 20 August 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9pn0 is ON HOLD until Paper Publication
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==Structure of HTTQ23-HAP40 complex bound to macrocycles HHL1, HD4 and HL2==
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<StructureSection load='9pn0' size='340' side='right'caption='[[9pn0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Balakrishnan, S., Deme, J., Lea, S.M., Harding, R.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9pn0]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PN0 FirstGlance]. <br>
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Description: Structure of HTTQ23-HAP40 complex bound to macrocycles HHL1, HD4 and HL2
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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[[Category: Balakrishnan, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pn0 OCA], [https://pdbe.org/9pn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pn0 RCSB], [https://www.ebi.ac.uk/pdbsum/9pn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pn0 ProSAT]</span></td></tr>
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[[Category: Lea, S.M]]
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</table>
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[[Category: Harding, R.J]]
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== Disease ==
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[[Category: Deme, J]]
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[https://www.uniprot.org/uniprot/HD_HUMAN HD_HUMAN] Juvenile Huntington disease;Huntington disease. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/HD_HUMAN HD_HUMAN] May play a role in microtubule-mediated transport or vesicle function.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Balakrishnan S]]
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[[Category: Deme J]]
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[[Category: Harding RJ]]
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[[Category: Lea SM]]

Current revision

Structure of HTTQ23-HAP40 complex bound to macrocycles HHL1, HD4 and HL2

PDB ID 9pn0

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