9n6h
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==2.54 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 1:1 complex== | |
| - | + | <StructureSection load='9n6h' size='340' side='right'caption='[[9n6h]], [[Resolution|resolution]] 2.54Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9n6h]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9N6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9N6H FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.54Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9n6h OCA], [https://pdbe.org/9n6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9n6h RCSB], [https://www.ebi.ac.uk/pdbsum/9n6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9n6h ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Armache J-P]] | ||
| + | [[Category: Bowman GD]] | ||
| + | [[Category: Folkwein HJ]] | ||
| + | [[Category: Nodelman IM]] | ||
Current revision
2.54 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 1:1 complex
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