9ih8
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==HSV-2 postfusion glycoprotein B== | |
| - | + | <StructureSection load='9ih8' size='340' side='right'caption='[[9ih8]], [[Resolution|resolution]] 2.21Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ih8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_2_strain_333 Human herpesvirus 2 strain 333]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IH8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.21Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ih8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ih8 OCA], [https://pdbe.org/9ih8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ih8 RCSB], [https://www.ebi.ac.uk/pdbsum/9ih8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ih8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GB_HHV23 GB_HHV23] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.[HAMAP-Rule:MF_04032] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human herpesvirus 2 strain 333]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ebel H]] | ||
| + | [[Category: Gruenewald K]] | ||
| + | [[Category: Mulvaney T]] | ||
| + | [[Category: Nentwig J]] | ||
| + | [[Category: Vollmer B]] | ||
Current revision
HSV-2 postfusion glycoprotein B
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