9q9l
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==HSV-1 prefusion glycoprotein B== | |
- | + | <StructureSection load='9q9l' size='340' side='right'caption='[[9q9l]], [[Resolution|resolution]] 2.64Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9q9l]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1_strain_17 Human alphaherpesvirus 1 strain 17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Q9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Q9L FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.64Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9q9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9q9l OCA], [https://pdbe.org/9q9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9q9l RCSB], [https://www.ebi.ac.uk/pdbsum/9q9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9q9l ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/A1Z0P7_HHV1 A1Z0P7_HHV1] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.[HAMAP-Rule:MF_04032] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Human alphaherpesvirus 1 strain 17]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Ebel H]] | ||
+ | [[Category: Gruenewald K]] | ||
+ | [[Category: Mulvaney T]] | ||
+ | [[Category: Nentwig J]] | ||
+ | [[Category: Vollmer B]] |
Current revision
HSV-1 prefusion glycoprotein B
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