9q9s
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==HSV-2 prefusion glycoprotein B bound by Nb1_gbHSV== | |
| - | + | <StructureSection load='9q9s' size='340' side='right'caption='[[9q9s]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9q9s]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_2_strain_333 Human herpesvirus 2 strain 333] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Q9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Q9S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9q9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9q9s OCA], [https://pdbe.org/9q9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9q9s RCSB], [https://www.ebi.ac.uk/pdbsum/9q9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9q9s ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GB_HHV23 GB_HHV23] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.[HAMAP-Rule:MF_04032] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human herpesvirus 2 strain 333]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vicugna pacos]] | ||
| + | [[Category: Ebel H]] | ||
| + | [[Category: Gruenewald K]] | ||
| + | [[Category: Mulvaney T]] | ||
| + | [[Category: Nentwig J]] | ||
| + | [[Category: Vollmer B]] | ||
Current revision
HSV-2 prefusion glycoprotein B bound by Nb1_gbHSV
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