9qky
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The structure of the DNA-binding domain of Nuclear Factor 1 X bound to NFI consensus DNA sequence== |
| - | + | <StructureSection load='9qky' size='340' side='right'caption='[[9qky]], [[Resolution|resolution]] 3.86Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9qky]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QKY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.86Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qky OCA], [https://pdbe.org/9qky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qky RCSB], [https://www.ebi.ac.uk/pdbsum/9qky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qky ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Gourlay | + | [https://www.uniprot.org/uniprot/NFIX_MOUSE NFIX_MOUSE] Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Isoform NFIX1 acts as a transcriptional activator while isoform NFIX3 acts as a repressor.<ref>PMID:8581067</ref> |
| - | [[Category: Tiberi | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Bonnet DMV]] | ||
| + | [[Category: Chaves-Sanjuan A]] | ||
| + | [[Category: Gourlay LJ]] | ||
| + | [[Category: Nardini M]] | ||
| + | [[Category: Tiberi M]] | ||
Current revision
The structure of the DNA-binding domain of Nuclear Factor 1 X bound to NFI consensus DNA sequence
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