9doa
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Membrane-bound OlyA/PlyB (Hinge-Lock) prepore== | |
- | + | <StructureSection load='9doa' size='340' side='right'caption='[[9doa]], [[Resolution|resolution]] 2.99Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9doa]] is a 39 chain structure with sequence from [https://en.wikipedia.org/wiki/Pleurotus_ostreatus Pleurotus ostreatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DOA FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.99Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9doa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9doa OCA], [https://pdbe.org/9doa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9doa RCSB], [https://www.ebi.ac.uk/pdbsum/9doa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9doa ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/OLYA6_PLEOS OLYA6_PLEOS] Has hemolytic activity against bovine erythrocytes at nanomolar concentrations in vitro. Promotes active pleurotolysin B (PlyB)-dependent permeabilization of membranes rich in cholesterol and sphingomyelin. May play an important role in the initial phase of fungal fruiting.<ref>PMID:12020804</ref> <ref>PMID:23806422</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Pleurotus ostreatus]] | ||
+ | [[Category: Chen Z]] | ||
+ | [[Category: Han Y]] | ||
+ | [[Category: Li Y]] | ||
+ | [[Category: Radhakrishnan A]] | ||
+ | [[Category: Smothers J]] |
Current revision
Membrane-bound OlyA/PlyB (Hinge-Lock) prepore
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