9qrl

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Current revision (05:48, 24 September 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9qrl is ON HOLD until Paper Publication
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==DNA polymerase with inhibitor #2==
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<StructureSection load='9qrl' size='340' side='right'caption='[[9qrl]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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Authors: Lamers, M.H., Urem, M., Smits, W.K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9qrl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QRL FirstGlance]. <br>
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Description: DNA polymerase with inhibitor #2
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1I9T:2-[(3,4-dichlorophenyl)methylamino]-7-(2-morpholin-4-ylethyl)-1~{H}-purin-6-one'>A1I9T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Smits, W.K]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qrl OCA], [https://pdbe.org/9qrl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qrl RCSB], [https://www.ebi.ac.uk/pdbsum/9qrl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qrl ProSAT]</span></td></tr>
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[[Category: Urem, M]]
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</table>
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[[Category: Lamers, M.H]]
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== Function ==
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[https://www.uniprot.org/uniprot/A0A9X4B319_ENTFC A0A9X4B319_ENTFC] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.[ARBA:ARBA00025611] Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.[ARBA:ARBA00003452][HAMAP-Rule:MF_00356]
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__TOC__
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</StructureSection>
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[[Category: Enterococcus faecium]]
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Lamers MH]]
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[[Category: Smits WK]]
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[[Category: Urem M]]

Current revision

DNA polymerase with inhibitor #2

PDB ID 9qrl

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