9u4e
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the human CRP-CPS23F complex== | |
| - | + | <StructureSection load='9u4e' size='340' side='right'caption='[[9u4e]], [[Resolution|resolution]] 2.78Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9u4e]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9U4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9U4E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.78Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EN6:1,3-bis(oxidanyl)propan-2-yl+[(2~{R},3~{S},4~{S},5~{R})-2-(hydroxymethyl)-3,5,6-tris(oxidanyl)oxan-4-yl]+hydrogen+phosphate'>A1EN6</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=RAM:ALPHA-L-RHAMNOSE'>RAM</scene>, <scene name='pdbligand=RM4:6-DEOXY-BETA-L-MANNOPYRANOSE'>RM4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9u4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9u4e OCA], [https://pdbe.org/9u4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9u4e RCSB], [https://www.ebi.ac.uk/pdbsum/9u4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9u4e ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Qi | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CRP_HUMAN CRP_HUMAN] Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| - | [[Category: Zhang | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen DY]] | ||
| + | [[Category: Gao F]] | ||
| + | [[Category: Qi JX]] | ||
| + | [[Category: Xie YF]] | ||
| + | [[Category: Zhang JR]] | ||
Current revision
Cryo-EM structure of the human CRP-CPS23F complex
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Categories: Homo sapiens | Large Structures | Chen DY | Gao F | Qi JX | Xie YF | Zhang JR
