9dsu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:47, 1 October 2025) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 9dsu is ON HOLD until Paper Publication
+
==Crystal structure of Fab 7088 in complex with N-terminal junction peptide from circumsporozoite protein==
-
 
+
<StructureSection load='9dsu' size='340' side='right'caption='[[9dsu]], [[Resolution|resolution]] 3.14&Aring;' scene=''>
-
Authors: Jain, M., Wilson, I.A.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[9dsu]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DSU FirstGlance]. <br>
-
Description: Crystal structure of Fab 7088 in complex with N-terminal junction peptide from circumsporozoite protein
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.14&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dsu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dsu OCA], [https://pdbe.org/9dsu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dsu RCSB], [https://www.ebi.ac.uk/pdbsum/9dsu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dsu ProSAT]</span></td></tr>
-
[[Category: Wilson, I.A]]
+
</table>
-
[[Category: Jain, M]]
+
== Function ==
 +
[https://www.uniprot.org/uniprot/CSP_PLAF7 CSP_PLAF7] Essential sporozoite protein (PubMed:29554084, PubMed:32150583). In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands (By similarity). In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes (PubMed:29554084, PubMed:32150583). Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes (By similarity).[UniProtKB:P23093]<ref>PMID:29554084</ref> <ref>PMID:32150583</ref> In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.[UniProtKB:P23093]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Plasmodium falciparum 3D7]]
 +
[[Category: Jain M]]
 +
[[Category: Wilson IA]]

Current revision

Crystal structure of Fab 7088 in complex with N-terminal junction peptide from circumsporozoite protein

PDB ID 9dsu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/9dsu"
Personal tools