9si3
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Chromosomal Passenger Complex in complex with H3T3ph Nucleosome== | |
- | + | <StructureSection load='9si3' size='340' side='right'caption='[[9si3]], [[Resolution|resolution]] 2.83Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9si3]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SI3 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.83Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9si3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9si3 OCA], [https://pdbe.org/9si3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9si3 RCSB], [https://www.ebi.ac.uk/pdbsum/9si3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9si3 ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
- | [[Category: | + | == Function == |
- | [[Category: Abad | + | [https://www.uniprot.org/uniprot/BOREA_HUMAN BOREA_HUMAN] Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.<ref>PMID:15260989</ref> <ref>PMID:15249581</ref> <ref>PMID:16571674</ref> <ref>PMID:18243099</ref> |
- | [[Category: Sotelo-Parrilla | + | == References == |
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Synthetic construct]] | ||
+ | [[Category: Xenopus laevis]] | ||
+ | [[Category: Abad MA]] | ||
+ | [[Category: Gireesh A]] | ||
+ | [[Category: Jeyaprakash AA]] | ||
+ | [[Category: Sotelo-Parrilla P]] |
Current revision
Chromosomal Passenger Complex in complex with H3T3ph Nucleosome
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