9c6z
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Staphylococcal Superantigen-Like protein 11 in complex with FB127== | |
| - | + | <StructureSection load='9c6z' size='340' side='right'caption='[[9c6z]], [[Resolution|resolution]] 2.14Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9c6z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9C6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9C6Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.137Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=A1AU2:(4aR,5S,6S,8R,8aS)-6-(hydroxymethyl)-8-methoxy-2,2-dimethylhexahydro-2H-pyrano[3,4-d][1,3]dioxin-5-ol'>A1AU2</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9c6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9c6z OCA], [https://pdbe.org/9c6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9c6z RCSB], [https://www.ebi.ac.uk/pdbsum/9c6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9c6z ProSAT]</span></td></tr> |
| - | [[Category: Birrane | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SLL11_STAAU SLL11_STAAU] Secreted protein that plays a role in the inhibition of host immune system. Targets myeloid cells such as monocytes or granulocytes through binding with sialyllactosamine-containing glycoproteins (PubMed:18045383). Prevents initial rolling of neutrophils toward the site of infection by interacting with host SELPLG (PubMed:18045383). Disrupts neutrophil motility by induction of cell adhesion via interacting with glycans but independently of SELPLG (PubMed:30862940).<ref>PMID:18045383</ref> <ref>PMID:30862940</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Birrane G]] | ||
| + | [[Category: Finton S]] | ||
Current revision
Crystal structure of Staphylococcal Superantigen-Like protein 11 in complex with FB127
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