9dt5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the engineered sulfonylurea repressor CsR (L4.2-20), bound to chlorsulfuron== | |
| - | + | <StructureSection load='9dt5' size='340' side='right'caption='[[9dt5]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9dt5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DT5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1CS:1-(2-CHLOROPHENYLSULFONYL)-3-(4-METHOXY-6-METHYL-L,3,5-TRIAZIN-2-YL)UREA'>1CS</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dt5 OCA], [https://pdbe.org/9dt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dt5 RCSB], [https://www.ebi.ac.uk/pdbsum/9dt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dt5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TETR2_ECOLX TETR2_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kakani NK]] | ||
| + | [[Category: Leija C]] | ||
| + | [[Category: Looger LL]] | ||
| + | [[Category: McBride KE]] | ||
| + | [[Category: Schreiter ER]] | ||
Current revision
Crystal structure of the engineered sulfonylurea repressor CsR (L4.2-20), bound to chlorsulfuron
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