9gw1

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m (Protected "9gw1" [edit=sysop:move=sysop])
Current revision (07:20, 8 October 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9gw1 is ON HOLD until Paper Publication
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==Cryo-EM structure of alpha-carboxysome T=4 mini-shell containing CTD only mutant of CsoSCA==
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<StructureSection load='9gw1' size='340' side='right'caption='[[9gw1]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors: Ng, P.C., Basle, A., Marles-Wright, J., Liu, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9gw1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Halothiobacillus_neapolitanus Halothiobacillus neapolitanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GW1 FirstGlance]. <br>
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Description: Cryo-EM structure of alpha-carboxysome T=4 mini-shell containing CTD only mutant of CsoSCA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gw1 OCA], [https://pdbe.org/9gw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gw1 RCSB], [https://www.ebi.ac.uk/pdbsum/9gw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gw1 ProSAT]</span></td></tr>
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[[Category: Marles-Wright, J]]
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</table>
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[[Category: Ng, P.C]]
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== Function ==
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[[Category: Liu, L]]
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[https://www.uniprot.org/uniprot/CSS4A_HALNC CSS4A_HALNC] Probably forms vertices in the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) is sequestered. Has been modeled to induce curvature upon insertion into an otherwise flat hexagonal layer of major carboxysome subunits (Probable). A minor shell protein, only 12 pentamers of CsoS4A/CsoS4B are calculated to be present in each carboxysome. The 2 CsoS4 proteins contribute to the impermeability of the carboxysome to CO(2) (PubMed:19844578).<ref>PMID:19844578</ref> <ref>PMID:18292340</ref> Unlike beta-carboxysomes, alpha-carboxysomes (Cb) can form without cargo protein. CsoS2 is essential for Cb formation and is also capable of targeting foreign proteins to the Cb. The Cb shell assembles with the aid of CsoS2; CsoS1A, CsoS1B and CsoS1C form the majority of the shell while CsoS4A and CsoS4B form vertices. CsoS1D forms pseudohexamers that probably control metabolite flux into and out of the shell.<ref>PMID:33116131</ref>
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[[Category: Basle, A]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Halothiobacillus neapolitanus]]
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[[Category: Large Structures]]
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[[Category: Basle A]]
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[[Category: Liu L]]
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[[Category: Marles-Wright J]]
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[[Category: Ng PC]]

Current revision

Cryo-EM structure of alpha-carboxysome T=4 mini-shell containing CTD only mutant of CsoSCA

PDB ID 9gw1

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