9uk3
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of WDR5 in complex with peptide Ac-MRTEPRPPAP-NH2== | |
| - | + | <StructureSection load='9uk3' size='340' side='right'caption='[[9uk3]], [[Resolution|resolution]] 1.69Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9uk3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UK3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9uk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9uk3 OCA], [https://pdbe.org/9uk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9uk3 RCSB], [https://www.ebi.ac.uk/pdbsum/9uk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9uk3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OSCRI_HUMAN OSCRI_HUMAN] Represses translation of the downstream SCRIB protein (PubMed:34535749). Translation of oSCRIB hinders SCRIB translation but does not completely abolish it, probably due to leaky scanning which allows the ribosome to bypass the weaker oSCRIB start codon and initiate translation at the stronger SCRIB start codon (PubMed:34535749).<ref>PMID:34535749</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen M-X]] | ||
| + | [[Category: Min J-R]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
Crystal structure of WDR5 in complex with peptide Ac-MRTEPRPPAP-NH2
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