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9i9i
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of CAK-CDK11== | |
| - | + | <StructureSection load='9i9i' size='340' side='right'caption='[[9i9i]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9i9i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9I9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9I9I FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9i9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9i9i OCA], [https://pdbe.org/9i9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9i9i RCSB], [https://www.ebi.ac.uk/pdbsum/9i9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9i9i ProSAT]</span></td></tr> |
| - | [[Category: Cushing | + | </table> |
| - | [[Category: Feng | + | == Function == |
| - | [[Category: Greber | + | [https://www.uniprot.org/uniprot/CD11B_HUMAN CD11B_HUMAN] Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.<ref>PMID:12501247</ref> <ref>PMID:12624090</ref> <ref>PMID:18216018</ref> <ref>PMID:2217177</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cushing VI]] | ||
| + | [[Category: Feng J]] | ||
| + | [[Category: Greber BJ]] | ||
| + | [[Category: McGeoch AJS]] | ||
Current revision
Cryo-EM structure of CAK-CDK11
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