9yd8
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of Phospholipase D (PLD) from Arcanobacterium haemolyticum== | |
- | + | <StructureSection load='9yd8' size='340' side='right'caption='[[9yd8]], [[Resolution|resolution]] 2.45Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9yd8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomycetaceae Actinomycetaceae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YD8 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9yd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yd8 OCA], [https://pdbe.org/9yd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yd8 RCSB], [https://www.ebi.ac.uk/pdbsum/9yd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yd8 ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
- | [[Category: Doherty | + | == Function == |
- | [[Category: | + | [https://www.uniprot.org/uniprot/PLD_ARCHD PLD_ARCHD] Virulence factor affecting bacterial dissemination and survival within the host. Has magnesium-dependent catalytic activity toward sphingomyelin (SM) and acyl- and alkyl-lysophosphatidylcholine (LPC), but not toward sphingosylphosphorylcholine (SPC) and phosphatidylcholine (PC). Lysophosphatidic acid (LPA), assumed to result from LPC hydrolysis, evokes pathophysiological responses after LPA receptor internalization. Shows hemolytic activity.[UniProtKB:P20626] |
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Actinomycetaceae]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Arni RK]] | ||
+ | [[Category: Doherty DZ]] | ||
+ | [[Category: Gismene C]] | ||
+ | [[Category: Nascimento AFZ]] |
Current revision
Crystal structure of Phospholipase D (PLD) from Arcanobacterium haemolyticum
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