9yd8

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m (Protected "9yd8" [edit=sysop:move=sysop])
Current revision (07:21, 15 October 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9yd8 is ON HOLD until 2027-03-22
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==Crystal structure of Phospholipase D (PLD) from Arcanobacterium haemolyticum==
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<StructureSection load='9yd8' size='340' side='right'caption='[[9yd8]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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Authors: Gismene, C., Doherty, D.Z., Nascimento, A.F.Z., Arni, R.K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9yd8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomycetaceae Actinomycetaceae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YD8 FirstGlance]. <br>
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Description: Crystal structure of Phospholipase D (PLD) from Arcanobacterium haemolyticum
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Nascimento, A.F.Z]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9yd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yd8 OCA], [https://pdbe.org/9yd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yd8 RCSB], [https://www.ebi.ac.uk/pdbsum/9yd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yd8 ProSAT]</span></td></tr>
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[[Category: Gismene, C]]
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</table>
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[[Category: Doherty, D.Z]]
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== Function ==
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[[Category: Arni, R.K]]
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[https://www.uniprot.org/uniprot/PLD_ARCHD PLD_ARCHD] Virulence factor affecting bacterial dissemination and survival within the host. Has magnesium-dependent catalytic activity toward sphingomyelin (SM) and acyl- and alkyl-lysophosphatidylcholine (LPC), but not toward sphingosylphosphorylcholine (SPC) and phosphatidylcholine (PC). Lysophosphatidic acid (LPA), assumed to result from LPC hydrolysis, evokes pathophysiological responses after LPA receptor internalization. Shows hemolytic activity.[UniProtKB:P20626]
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__TOC__
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</StructureSection>
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[[Category: Actinomycetaceae]]
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[[Category: Large Structures]]
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[[Category: Arni RK]]
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[[Category: Doherty DZ]]
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[[Category: Gismene C]]
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[[Category: Nascimento AFZ]]

Current revision

Crystal structure of Phospholipase D (PLD) from Arcanobacterium haemolyticum

PDB ID 9yd8

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