9dz7

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Current revision (09:06, 22 October 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9dz7 is ON HOLD until Paper Publication
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==Structure of ALAS bound to glycine from S. cerevisiae==
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<StructureSection load='9dz7' size='340' side='right'caption='[[9dz7]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
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Authors: Tran, J.U., Brown, B.L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9dz7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DZ7 FirstGlance]. <br>
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Description: Structure of ALAS bound to glycine from S. cerevisiae
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.487&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PLG:N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]'>PLG</scene></td></tr>
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[[Category: Tran, J.U]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dz7 OCA], [https://pdbe.org/9dz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dz7 RCSB], [https://www.ebi.ac.uk/pdbsum/9dz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dz7 ProSAT]</span></td></tr>
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[[Category: Brown, B.L]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HEM1_YEAST HEM1_YEAST] Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.<ref>PMID:6381051</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Brown BL]]
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[[Category: Tran JU]]

Current revision

Structure of ALAS bound to glycine from S. cerevisiae

PDB ID 9dz7

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