9i3f

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Current revision (09:10, 22 October 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9i3f is ON HOLD until Paper Publication
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==Crystal structure of the AGR2 and IRE1beta_loop complex==
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<StructureSection load='9i3f' size='340' side='right'caption='[[9i3f]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: Yan, Y., Ron, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9i3f]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9I3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9I3F FirstGlance]. <br>
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Description: Crystal structure of the AGR2 and IRE1beta_loop complex
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Yan, Y]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9i3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9i3f OCA], [https://pdbe.org/9i3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9i3f RCSB], [https://www.ebi.ac.uk/pdbsum/9i3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9i3f ProSAT]</span></td></tr>
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[[Category: Ron, D]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ERN2_HUMAN ERN2_HUMAN] Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.<ref>PMID:11175748</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Ron D]]
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[[Category: Yan Y]]

Current revision

Crystal structure of the AGR2 and IRE1beta_loop complex

PDB ID 9i3f

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