9m1k

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Current revision (09:18, 22 October 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9m1k is ON HOLD until Paper Publication
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==Cryo-EM structure of the TBC-DE-Arl2-beta-tubulin complex with GTP==
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<StructureSection load='9m1k' size='340' side='right'caption='[[9m1k]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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Authors: Seong, Y.J., Kim, H.M., Byun, K.M., Park, Y.W., Roh, S.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9m1k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9M1K FirstGlance]. <br>
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Description: Cryo-EM structure of the TBC-DE-Arl2-beta-tubulin complex with GTP
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Roh, S.H]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9m1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m1k OCA], [https://pdbe.org/9m1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m1k RCSB], [https://www.ebi.ac.uk/pdbsum/9m1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m1k ProSAT]</span></td></tr>
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[[Category: Kim, H.M]]
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</table>
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[[Category: Park, Y.W]]
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== Disease ==
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[[Category: Byun, K.M]]
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[https://www.uniprot.org/uniprot/TBCE_HUMAN TBCE_HUMAN] Sanjad-Sakati syndrome;Autosomal recessive Kenny-Caffey syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Seong, Y.J]]
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== Function ==
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[https://www.uniprot.org/uniprot/TBCE_HUMAN TBCE_HUMAN] Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation.<ref>PMID:11847227</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Sus scrofa]]
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[[Category: Byun KM]]
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[[Category: Kim HM]]
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[[Category: Park YW]]
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[[Category: Roh SH]]
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[[Category: Seong YJ]]

Current revision

Cryo-EM structure of the TBC-DE-Arl2-beta-tubulin complex with GTP

PDB ID 9m1k

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OCA

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