9m46
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of IQSEC2 CC domain== | |
| - | + | <StructureSection load='9m46' size='340' side='right'caption='[[9m46]], [[Resolution|resolution]] 1.77Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9m46]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9M46 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9m46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m46 OCA], [https://pdbe.org/9m46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m46 RCSB], [https://www.ebi.ac.uk/pdbsum/9m46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m46 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/IQEC2_HUMAN IQEC2_HUMAN] Severe intellectual disability-progressive postnatal microcephaly- midline stereotypic hand movements syndrome;X-linked non-syndromic intellectual disability. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IQEC2_HUMAN IQEC2_HUMAN] Is a guanine nucleotide exchange factor for the ARF GTP-binding proteins.<ref>PMID:26793055</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bai G]] | ||
| + | [[Category: Cai Q]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
Crystal structure of IQSEC2 CC domain
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Categories: Homo sapiens | Large Structures | Bai G | Cai Q | Zhang M
