9r6z

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m (Protected "9r6z" [edit=sysop:move=sysop])
Current revision (09:24, 22 October 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9r6z is ON HOLD until Paper Publication
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==Cubic state of the F420-reducing hydrogenase from Methanothermococcus thermolithotrophicus==
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<StructureSection load='9r6z' size='340' side='right'caption='[[9r6z]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9r6z]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermococcus_thermolithotrophicus_DSM_2095 Methanothermococcus thermolithotrophicus DSM 2095]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9R6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9R6Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NFU:FORMYL[BIS(HYDROCYANATO-1KAPPAC)]IRONNICKEL(FE-NI)'>NFU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9r6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9r6z OCA], [https://pdbe.org/9r6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9r6z RCSB], [https://www.ebi.ac.uk/pdbsum/9r6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9r6z ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Hydrogenases catalyze reversible H(2) production and are potential models for renewable energy catalysts. Here, the full redox landscape of a group 3 [NiFe]-hydrogenase from methanothermococcus thermolithotrophicus is elucidated, resembling group 1 enzymes. Structural and spectroscopic analyses reveal a catalytic-ready state with nickel seesaw coordination, enabling intermediate trapping and advancing mechanistic understanding of oxygen-sensitive [NiFe] enzymes.
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Authors: Jespersen, M., Lemaire, O.N., Wagner, T.
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Structural and Spectroscopic Insights into Catalytic Intermediates of a [NiFe]-hydrogenase from Group 3.,Jespersen M, Lorent C, Lemaire ON, Zebger I, Wagner T Chembiochem. 2025 Oct 13:e202500692. doi: 10.1002/cbic.202500692. PMID:41078086<ref>PMID:41078086</ref>
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Description: Cubic state of the F420-reducing hydrogenase from Methanothermococcus thermolithotrophicus
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Jespersen, M]]
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<div class="pdbe-citations 9r6z" style="background-color:#fffaf0;"></div>
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[[Category: Lemaire, O.N]]
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== References ==
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[[Category: Wagner, T]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Methanothermococcus thermolithotrophicus DSM 2095]]
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[[Category: Jespersen M]]
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[[Category: Lemaire ON]]
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[[Category: Wagner T]]

Current revision

Cubic state of the F420-reducing hydrogenase from Methanothermococcus thermolithotrophicus

PDB ID 9r6z

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