Leukotriene A4 Hydrolase
From Proteopedia
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**[[3fue]], [[3fuf]], [[3fuh]] - hLTA4H+bestatin+indole derivative<br /> | **[[3fue]], [[3fuf]], [[3fuh]] - hLTA4H+bestatin+indole derivative<br /> | ||
**[[3fuj]], [[3fuk]] - hLTA4H+indole derivative<br /> | **[[3fuj]], [[3fuk]] - hLTA4H+indole derivative<br /> | ||
| - | **[[3b7r]], [[3cho]], [[3chp]], [[3chq]], [[3chr]], [[3chs]], [[2r59]], [[3u9w]], [[4r7l]], [[4rsy]], [[5aen]], [[5bpp]], [[6enc]], [[6end]], [[7auz]], [[7av0]], [[7av1]], [[7av2]], [[8ava]], [[8awh]] - hLTA4H+inhibitor<br /> | + | **[[3b7r]], [[3cho]], [[3chp]], [[3chq]], [[3chr]], [[3chs]], [[2r59]], [[3u9w]], [[4r7l]], [[4rsy]], [[5aen]], [[5bpp]], [[6enc]], [[6end]], [[7auz]], [[7av0]], [[7av1]], [[7av2]], [[8ava]], [[8awh]], [[8twx]] - hLTA4H+inhibitor<br /> |
**[[3b7u]] - hLTA4H+kelatorphan <br /> | **[[3b7u]] - hLTA4H+kelatorphan <br /> | ||
**[[2vj8]] - hLTA4H+hydroxamic acid<br /> | **[[2vj8]] - hLTA4H+hydroxamic acid<br /> | ||
Current revision
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3D Structures of Leukotriene A4 Hydrolase
Updated on 26-October-2025
References
- ↑ Paige M, Wang K, Burdick M, Park S, Cha J, Jeffery E, Sherman N, Shim YM. Role of leukotriene A4 hydrolase aminopeptidase in the pathogenesis of emphysema. J Immunol. 2014 Jun 1;192(11):5059-68. doi: 10.4049/jimmunol.1400452. Epub 2014, Apr 25. PMID:24771855 doi:http://dx.doi.org/10.4049/jimmunol.1400452
- ↑ Fourie AM. Modulation of inflammatory disease by inhibitors of leukotriene A4 hydrolase. Curr Opin Investig Drugs. 2009 Nov;10(11):1173-82. PMID:19876785
- ↑ Thunnissen MM, Nordlund P, Haeggstrom JZ. Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation. Nat Struct Biol. 2001 Feb;8(2):131-5. PMID:11175901 doi:10.1038/84117
