9ezh
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of single-domain antibody VHH_h4 in complex with human Vsig4== | |
| - | + | <StructureSection load='9ezh' size='340' side='right'caption='[[9ezh]], [[Resolution|resolution]] 1.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ezh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelidae Camelidae] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EZH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ezh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ezh OCA], [https://pdbe.org/9ezh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ezh RCSB], [https://www.ebi.ac.uk/pdbsum/9ezh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ezh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VSIG4_HUMAN VSIG4_HUMAN] Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.<ref>PMID:17016562</ref> <ref>PMID:17051150</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Camelidae]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cianferoni D]] | ||
| + | [[Category: Delgado J]] | ||
| + | [[Category: Dewilde M]] | ||
| + | [[Category: Garcia T]] | ||
| + | [[Category: Maragkou K]] | ||
| + | [[Category: Rousseau F]] | ||
| + | [[Category: Schymkowitz J]] | ||
| + | [[Category: Serrano L]] | ||
| + | [[Category: Vizarraga D]] | ||
| + | [[Category: Zhang Z]] | ||
| + | [[Category: Van der Kant R]] | ||
Current revision
Structure of single-domain antibody VHH_h4 in complex with human Vsig4
| |||||||||||
Categories: Camelidae | Homo sapiens | Large Structures | Cianferoni D | Delgado J | Dewilde M | Garcia T | Maragkou K | Rousseau F | Schymkowitz J | Serrano L | Vizarraga D | Zhang Z | Van der Kant R
