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9haq

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Current revision (07:23, 12 November 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9haq is ON HOLD until Paper Publication
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==Crystal structure of methionine gamma-lyase from Brevibacterium sandarakinum in complex with PLP and norleucine at pH 8.5==
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<StructureSection load='9haq' size='340' side='right'caption='[[9haq]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
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Authors: Kopecny, D., Ferchaud, N., Briozzo, P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9haq]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacterium Brevibacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HAQ FirstGlance]. <br>
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Description: Crystal structure of methionine gamma-lyase from Brevibacterium sandarakinum in complex with PLP and norleucine at pH 8.5
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.693&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PY6:2-[O-PHOSPHONOPYRIDOXYL]-AMINO-HEXANOIC+ACID'>PY6</scene></td></tr>
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[[Category: Briozzo, P]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9haq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9haq OCA], [https://pdbe.org/9haq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9haq RCSB], [https://www.ebi.ac.uk/pdbsum/9haq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9haq ProSAT]</span></td></tr>
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[[Category: Ferchaud, N]]
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</table>
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[[Category: Kopecny, D]]
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== Function ==
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[https://www.uniprot.org/uniprot/MEGL_BRESA MEGL_BRESA] Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia. Is also able to catalyze the alpha,gamma-elimination of L-homocysteine.[UniProtKB:A0A2H1K3G9]
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__TOC__
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</StructureSection>
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[[Category: Brevibacterium]]
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[[Category: Large Structures]]
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[[Category: Briozzo P]]
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[[Category: Ferchaud N]]
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[[Category: Kopecny D]]

Current revision

Crystal structure of methionine gamma-lyase from Brevibacterium sandarakinum in complex with PLP and norleucine at pH 8.5

PDB ID 9haq

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