We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
9lxh
From Proteopedia
(Difference between revisions)
m (Protected "9lxh" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==DOCK5/ELMO1 complex with RhoG and Rac1 on lipid membrane== | |
| - | + | <StructureSection load='9lxh' size='340' side='right'caption='[[9lxh]], [[Resolution|resolution]] 7.52Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9lxh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9LXH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.52Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9lxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9lxh OCA], [https://pdbe.org/9lxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9lxh RCSB], [https://www.ebi.ac.uk/pdbsum/9lxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9lxh ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ELMO1_HUMAN ELMO1_HUMAN] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.<ref>PMID:11595183</ref> <ref>PMID:12134158</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Katsura K]] | ||
| + | [[Category: Kukimoto-Niino M]] | ||
| + | [[Category: Shinoda T]] | ||
| + | [[Category: Shirouzu M]] | ||
Current revision
DOCK5/ELMO1 complex with RhoG and Rac1 on lipid membrane
| |||||||||||
