9me7

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Current revision (06:27, 26 November 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9me7 is ON HOLD until Paper Publication
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==Antibody fragments from mAb21 and mAb824 bound to the adhesin protein FimH containing alpha-methyl mannose==
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<StructureSection load='9me7' size='340' side='right'caption='[[9me7]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9me7]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ME7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ME7 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9me7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9me7 OCA], [https://pdbe.org/9me7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9me7 RCSB], [https://www.ebi.ac.uk/pdbsum/9me7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9me7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Hvorecny KL]]
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[[Category: Klevit RE]]
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[[Category: Kollman JM]]
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[[Category: Magala P]]

Current revision

Antibody fragments from mAb21 and mAb824 bound to the adhesin protein FimH containing alpha-methyl mannose

PDB ID 9me7

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