9m2e

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Current revision (19:23, 4 December 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9m2e is ON HOLD until Paper Publication
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==Crystal Structure of Nur77 LBD in complex with DBIC compound==
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<StructureSection load='9m2e' size='340' side='right'caption='[[9m2e]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
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Authors: Hong, W.B., Lin, T.W., Chen, X.Q., Wu, Q.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9m2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9M2E FirstGlance]. <br>
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Description: Crystal Structure of Nur77 LBD in complex with DBIC compound
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.575&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1D7W:dodecyl+1~{H}-benzimidazole-5-carboxylate'>A1D7W</scene></td></tr>
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[[Category: Hong, W.B]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9m2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m2e OCA], [https://pdbe.org/9m2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m2e RCSB], [https://www.ebi.ac.uk/pdbsum/9m2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m2e ProSAT]</span></td></tr>
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[[Category: Lin, T.W]]
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</table>
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[[Category: Wu, Q]]
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== Function ==
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[[Category: Chen, X.Q]]
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[https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen XQ]]
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[[Category: Hong WB]]
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[[Category: Lin TW]]
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[[Category: Wu Q]]

Current revision

Crystal Structure of Nur77 LBD in complex with DBIC compound

PDB ID 9m2e

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