9bbj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==M. tuberculosis ClpC1-NTD complexed with a click chemistry analog of Rufomycin== | |
| - | + | <StructureSection load='9bbj' size='340' side='right'caption='[[9bbj]], [[Resolution|resolution]] 2.56Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9bbj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BBJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AL8:1-(2-methylbut-3-en-2-yl)-L-tryptophan'>A1AL8</scene>, <scene name='pdbligand=A1AMB:(2~{S})-2-azanyl-3-(1,2,3-triazol-1-yl)propanoic+acid'>A1AMB</scene>, <scene name='pdbligand=A1AMC:5-hydroxy-N-methyl-L-norvaline'>A1AMC</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9bbj OCA], [https://pdbe.org/9bbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9bbj RCSB], [https://www.ebi.ac.uk/pdbsum/9bbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9bbj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CLPC1_MYCTU CLPC1_MYCTU] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Abad-Zapatero C]] | ||
| + | [[Category: Ratia K]] | ||
Current revision
M. tuberculosis ClpC1-NTD complexed with a click chemistry analog of Rufomycin
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