9shj

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Current revision (08:22, 11 December 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9shj is ON HOLD until Paper Publication
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==ATP-bound human mitochondrial Hsp60-Hsp10 double-ring complex (D7)==
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<StructureSection load='9shj' size='340' side='right'caption='[[9shj]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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Authors: Lopez-Alonso, J.P., Tascon, I., Ubarretxena-Belandia, I.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9shj]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SHJ FirstGlance]. <br>
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Description: ATP-bound human mitochondrial Hsp60-Hsp10 double-ring complex (D7)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Lopez-Alonso, J.P]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9shj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9shj OCA], [https://pdbe.org/9shj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9shj RCSB], [https://www.ebi.ac.uk/pdbsum/9shj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9shj ProSAT]</span></td></tr>
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[[Category: Ubarretxena-Belandia, I]]
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</table>
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[[Category: Tascon, I]]
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== Disease ==
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[https://www.uniprot.org/uniprot/CH60_HUMAN CH60_HUMAN] Autosomal dominant spastic paraplegia type 13;Pelizaeus-Merzbacher-like disease due to HSPD1 mutation. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/CH60_HUMAN CH60_HUMAN] Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Lopez-Alonso JP]]
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[[Category: Tascon I]]
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[[Category: Ubarretxena-Belandia I]]

Current revision

ATP-bound human mitochondrial Hsp60-Hsp10 double-ring complex (D7)

PDB ID 9shj

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