Methionine synthase 3D structures

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Current revision (10:46, 21 December 2025) (edit) (undo)
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*Cobalamin-dependent Methionine synthase
 
-
**[[2o2k]] – hMetH activation domain 926-1265 (mutant) – human<br />
+
*Cobalamin-dependent methionine synthase; Domains – homocysteine 17-352; folate-binding 353-648; cobalamine-binding 650-895; activation domain 926-1265
-
**[[1j6r]] – TmMetH activation domain 1-202 – ''Thermotoga maritima''<br />
+
 
 +
**[[9ssu]], [[9ssv]] – hMetH – human - Cryo EM<br />
 +
**[[2o2k]] – hMetH activation domain (mutant) <br />
 +
**[[8ssd]], [[8sse]] – hMetH cobalamine+activation domains<br />
 +
**[[1j6r]] – TmMetH activation domain 1-202 – Thermotoga maritima<br />
**[[1q7m]], [[1q7q]], [[1q7z]], [[1q85]], [[1q8a]] – TmMetH 1-566 <br />
**[[1q7m]], [[1q7q]], [[1q7z]], [[1q85]], [[1q8a]] – TmMetH 1-566 <br />
-
**[[5von]] – TtMetH folate-binding domain 353-648 – ''Thermus thermophilus'' <br />
+
**[[8ssc]] – TtMetH – Thermus thermophilus <br />
-
**[[4ztx]], [[4zty]] – MetH – Neurospora crassa <br />
+
**[[5von]] – TtMetH folate-binding domain <br />
-
**[[3k13]] – MetH pterin-binding domain 353-648 – ''Bacterioides thetaiotaomicron''<br />
+
**[[4ztx]], [[]4zty]] – MetH – Neurospora crassa <br />
 +
**[[3k13]] – MetH folate-binding domain – Bacterioides thetaiotaomicron<br />
*Methionine synthase binary complex
*Methionine synthase binary complex
-
**[[4ccz]] – hMetH homocysteine and folate-binding domain 16-657 + folate derivative <br />
+
**[[9ssp]], [[9ssq]], [[9ssr]] – hMetH + folate derivative – Cryo EM<br />
-
**[[1k7y]], [[1k98]], [[3bul]], [[3iv9]] – EcMetH activation domain 651-1227 (mutant) + cobalamine – ''Escherichia coli''<br />
+
**[[9sss]] – hMetH + cobalabine – Cryo EM<br />
-
**[[8g3h]] – MetH + cobalamine – ''Thermus filiformis''<br />
+
**[[4ccz]] – hMetH homocysteine and folate-binding domain + folate derivative <br />
 +
**[[1k7y]], [[1k98]], [[3bul]], [[3iv9]] – EcMetH cobalamine-binding and activation domain (mutant) + cobalamine – Escherichia coli<br />
 +
**[[8g3h]] – MetH + cobalamine – Thermus filiformis<br />
**[[1msk]], [[6bm5]] – EcMetH activation domain + SAM<br />
**[[1msk]], [[6bm5]] – EcMetH activation domain + SAM<br />
-
**[[6bm6]] – EcMetH activation domain + SAH<br />
+
**[6bm6]] – EcMetH activation domain + SAH<br />
**[[6bdy]] – EcMetH activation domain + sinefugin<br />
**[[6bdy]] – EcMetH activation domain + sinefugin<br />
-
**[[1bmt]] – EcMetH cobalamine-binding domain 650-895 + cobalamine <br />
+
**[[1bmt]] – EcMetH cobalamine-binding domain + cobalamine <br />
**[[3bof]], [[3bol]] – TmMetH 1-566 + homocysteine<br />
**[[3bof]], [[3bol]] – TmMetH 1-566 + homocysteine<br />
**[[5voo]], [[5vop]] – TtMetH folate-binding domain + folate derivative <br />
**[[5voo]], [[5vop]] – TtMetH folate-binding domain + folate derivative <br />
 +
**[[9sst]] – TtMetH + cobalamine – Cryo EM<br />
 +
**[[9cbo]], [[9cbq]] – TtMetH folate+cobalamine-binding domains + cobalamine<br />
 +
**[[9cbp]] – TtMetH homocysteine+folate+cobalamine-binding domains + cobalamine<br />
 +
**[[9cbr]] – TtMetH homocysteine+folate+cobalamine-binding domains (mutant) + cobalamine<br />
*Methionine synthase ternary complex
*Methionine synthase ternary complex
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*Cobalamin-independent methionine synthase
*Cobalamin-independent methionine synthase
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**[[1u1u]] – AtMetH – ''Arabidopsis thaliana''<br />
+
**[[1u1u]] – AtMetH – Arabidopsis thaliana<br />
**[[1u1h]] – AtMetH + Met<br />
**[[1u1h]] – AtMetH + Met<br />
**[[1u22]] – AtMetH + folate derivative <br />
**[[1u22]] – AtMetH + folate derivative <br />
**[[1u1j]] – AtMetH + folate derivative + Met<br />
**[[1u1j]] – AtMetH + folate derivative + Met<br />
-
**[[3rpd]] – MetH 1-354 - ''Shewanella'' <br />
+
**[[3rpd]] – MetH homocysteine domain - Shewanella <br />
-
**[[2nq5]], [[3l7r]], [[3t0c]] – MetH – ''Streptococcus mutans''<br />
+
**[[2nq5]], [[3l7r]], [[3t0c]] – MetH – Streptococcus mutans<br />
**[[1t7l]] – TmMetH 1-566 <br />
**[[1t7l]] – TmMetH 1-566 <br />
**[[3bq6]] – TmMetH 2-734 <br />
**[[3bq6]] – TmMetH 2-734 <br />
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**[[1xdj]], [[3bq5]] – TmMetH 1-566 + homocysteine<br />
**[[1xdj]], [[3bq5]] – TmMetH 1-566 + homocysteine<br />
**[[1xpg]] – TmMetH 1-566 + folate derivative <br />
**[[1xpg]] – TmMetH 1-566 + folate derivative <br />
-
**[[3ppc]], [[3ppf]], [[3ppg]], [[3pph]] – CaMetH (mutant) – ''Candida albicans<''br />
+
**[[3ppc]], [[3ppf]], [[3ppg]], [[3pph]] – CaMetH (mutant) – Candida albicans<br />
**[[4l5z]], [[4l64]] – CaMetH (mutant) + homocysteine<br />
**[[4l5z]], [[4l64]] – CaMetH (mutant) + homocysteine<br />
**[[4qqu]] – CaMetH (mutant) + homocysteine<br />
**[[4qqu]] – CaMetH (mutant) + homocysteine<br />
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**[[4l65]] – CaMetH (mutant) + folate derivative + Met<br />
**[[4l65]] – CaMetH (mutant) + folate derivative + Met<br />
**[[4l6h]] – CaMetH (mutant) + methotrexate + homocysteine<br />
**[[4l6h]] – CaMetH (mutant) + methotrexate + homocysteine<br />
 +
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Methionine synthase

Updated on 21-December-2025

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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