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2aaq
From Proteopedia
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(New page: 200px<br /> <applet load="2aaq" size="450" color="white" frame="true" align="right" spinBox="true" caption="2aaq, resolution 2.60Å" /> '''Crystal Structure A...)
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Revision as of 18:41, 12 November 2007
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Crystal Structure Analysis of the human Glutahione Reductase, complexed with GoPI
Disease
Known disease associated with this structure: Hemolytic anemia due to glutathione reductase deficiency OMIM:[138300]
About this Structure
2AAQ is a Single protein structure of sequence from Homo sapiens with PO4, CL, K, FAD, AUP, AU and GOL as ligands. Active as Glutathione-disulfide reductase, with EC number 1.8.1.7 Full crystallographic information is available from OCA.
Reference
Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases., Urig S, Fritz-Wolf K, Reau R, Herold-Mende C, Toth K, Davioud-Charvet E, Becker K, Angew Chem Int Ed Engl. 2006 Mar 13;45(12):1881-6. PMID:16493712
Page seeded by OCA on Mon Nov 12 20:48:06 2007
Categories: Glutathione-disulfide reductase | Homo sapiens | Single protein | Becker, K. | Davioud-Charvet, E. | Fritz-Wolf, K. | Herold-Mende, C. | Reau, R. | Toth, K. | Urig, S. | AU | AUP | CL | FAD | GOL | K | PO4 | Antioxidative system | Disulfide reductase | Glutathione reduction | Gold-coordination | Homodimer | Protein gold complex
