9jf3

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m (Protected "9jf3" [edit=sysop:move=sysop])
Current revision (05:15, 24 December 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9jf3 is ON HOLD
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==The complex structure of 0086-0043 and NET determined with Cryo-EM.==
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<StructureSection load='9jf3' size='340' side='right'caption='[[9jf3]], [[Resolution|resolution]] 2.87&Aring;' scene=''>
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Authors: Jia, Y.J., Gao, B., Tan, J.X., Yan, C.Y., Zhang, W., Lan, Y.Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9jf3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JF3 FirstGlance]. <br>
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Description: The complex structure of 0086-0043 and NET determined with Cryo-EM.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.87&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EBO:2-isoquinolin-2-ium-2-yl-1-phenyl-ethanone'>A1EBO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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[[Category: Yan, C.Y]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jf3 OCA], [https://pdbe.org/9jf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jf3 RCSB], [https://www.ebi.ac.uk/pdbsum/9jf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jf3 ProSAT]</span></td></tr>
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[[Category: Lan, Y.Y]]
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</table>
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[[Category: Jia, Y.J]]
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== Disease ==
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[[Category: Tan, J.X]]
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[https://www.uniprot.org/uniprot/SC6A2_HUMAN SC6A2_HUMAN] Postural orthostatic tachycardia syndrome due to NET deficiency. The disease is caused by variants affecting the gene represented in this entry.
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[[Category: Zhang, W]]
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== Function ==
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[[Category: Gao, B]]
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[https://www.uniprot.org/uniprot/SC6A2_HUMAN SC6A2_HUMAN] Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (PubMed:2008212, PubMed:8125921). Can also mediate sodium- and chloride-dependent transport of dopamine (PubMed:11093780, PubMed:8125921).<ref>PMID:11093780</ref> <ref>PMID:2008212</ref> <ref>PMID:8125921</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Gao B]]
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[[Category: Jia YJ]]
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[[Category: Lan YY]]
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[[Category: Tan JX]]
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[[Category: Yan CY]]
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[[Category: Zhang W]]

Current revision

The complex structure of 0086-0043 and NET determined with Cryo-EM.

PDB ID 9jf3

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OCA

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