9u3s
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human AC9 (TM domain)== | |
| - | + | <StructureSection load='9u3s' size='340' side='right'caption='[[9u3s]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9u3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_orthopneumovirus Human orthopneumovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9U3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9U3S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9u3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9u3s OCA], [https://pdbe.org/9u3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9u3s RCSB], [https://www.ebi.ac.uk/pdbsum/9u3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9u3s ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ADCY9_HUMAN ADCY9_HUMAN] Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors (PubMed:10987815, PubMed:12972952, PubMed:15879435, PubMed:9628827). Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors (PubMed:9628827).<ref>PMID:10987815</ref> <ref>PMID:12972952</ref> <ref>PMID:15879435</ref> <ref>PMID:9628827</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Human orthopneumovirus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fujiyoshi Y]] | ||
| + | [[Category: Nishikawa K]] | ||
| + | [[Category: Nomura R]] | ||
| + | [[Category: Suzuki H]] | ||
| + | [[Category: Suzuki S]] | ||
Current revision
Cryo-EM structure of human AC9 (TM domain)
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