9xvd

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Current revision (07:16, 31 December 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9xvd is ON HOLD until Paper Publication
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==Crystal structure of NFIC homodimer bound to DNA==
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<StructureSection load='9xvd' size='340' side='right'caption='[[9xvd]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Pan, S.L., Min, J.R., Liu, K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9xvd]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9XVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9XVD FirstGlance]. <br>
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Description: Crystal structure of NFIC homodimer bound to DNA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Pan, S.L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9xvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9xvd OCA], [https://pdbe.org/9xvd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9xvd RCSB], [https://www.ebi.ac.uk/pdbsum/9xvd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9xvd ProSAT]</span></td></tr>
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[[Category: Min, J.R]]
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</table>
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[[Category: Liu, K]]
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== Function ==
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[https://www.uniprot.org/uniprot/NFIC_HUMAN NFIC_HUMAN] Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Liu K]]
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[[Category: Min JR]]
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[[Category: Pan SL]]

Current revision

Crystal structure of NFIC homodimer bound to DNA

PDB ID 9xvd

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