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9l65
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures== | |
| - | + | <StructureSection load='9l65' size='340' side='right'caption='[[9l65]], [[Resolution|resolution]] 1.99Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9l65]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L65 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EJN:[2,5-bis(oxidanylidene)pyrrolidin-1-yl]+18-(2,3-dimethylimidazol-1-ium-1-yl)octadecanoate'>A1EJN</scene></td></tr> |
| - | [[Category: Fang | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l65 OCA], [https://pdbe.org/9l65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l65 RCSB], [https://www.ebi.ac.uk/pdbsum/9l65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l65 ProSAT]</span></td></tr> |
| - | [[Category: Jiang | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FUT8_HUMAN FUT8_HUMAN] Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.<ref>PMID:9133635</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fang P]] | ||
| + | [[Category: Jiang J]] | ||
Current revision
A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures
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