1xnq

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[[Image:1xnq.gif|left|200px]]
[[Image:1xnq.gif|left|200px]]
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{{Structure
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|PDB= 1xnq |SIZE=350|CAPTION= <scene name='initialview01'>1xnq</scene>, resolution 3.05&Aring;
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The line below this paragraph, containing "STRUCTURE_1xnq", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=I:INOSINIC+ACID'>I</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PAR:PAROMOMYCIN'>PAR</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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{{STRUCTURE_1xnq| PDB=1xnq | SCENE= }}
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|RELATEDENTRY=[[1xmo|1XMO]], [[1xmq|1XMQ]], [[1ibl|1IBL]], [[1ibm|1IBM]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xnq OCA], [http://www.ebi.ac.uk/pdbsum/1xnq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xnq RCSB]</span>
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'''Structure of an Inosine-Adenine Wobble Base Pair Complex in the Context of the Decoding Center'''
'''Structure of an Inosine-Adenine Wobble Base Pair Complex in the Context of the Decoding Center'''
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[[Category: Murphy, F V.]]
[[Category: Murphy, F V.]]
[[Category: Ramakrishnan, V.]]
[[Category: Ramakrishnan, V.]]
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[[Category: decoding]]
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[[Category: Decoding]]
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[[Category: inosine]]
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[[Category: Inosine]]
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[[Category: ribosome]]
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[[Category: Ribosome]]
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[[Category: translation]]
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[[Category: Translation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:16:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:52:11 2008''
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Revision as of 12:16, 3 May 2008

Image:1xnq.gif

Template:STRUCTURE 1xnq

Structure of an Inosine-Adenine Wobble Base Pair Complex in the Context of the Decoding Center


Overview

Here we report the crystal structures of I.C and I.A wobble base pairs in the context of the ribosomal decoding center, clearly showing that the I.A base pair is of an I(anti).A(anti) conformation, as predicted by Crick. Additionally, the structures enable the observation of changes in the anticodon to allow purine-purine base pairing, the 'widest' base pair geometry allowed in the wobble position.

About this Structure

1XNQ is a Protein complex structure of sequences from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Structure of a purine-purine wobble base pair in the decoding center of the ribosome., Murphy FV 4th, Ramakrishnan V, Nat Struct Mol Biol. 2004 Dec;11(12):1251-2. Epub 2004 Nov 21. PMID:15558050 Page seeded by OCA on Sat May 3 15:16:19 2008

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