1zoq

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[[Image:1zoq.gif|left|200px]]
[[Image:1zoq.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1zoq |SIZE=350|CAPTION= <scene name='initialview01'>1zoq</scene>, resolution 2.37&Aring;
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The line below this paragraph, containing "STRUCTURE_1zoq", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND=
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= IRF3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CREBBP, CBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_1zoq| PDB=1zoq | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zoq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zoq OCA], [http://www.ebi.ac.uk/pdbsum/1zoq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1zoq RCSB]</span>
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}}
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'''IRF3-CBP complex'''
'''IRF3-CBP complex'''
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[[Category: Lin, K.]]
[[Category: Lin, K.]]
[[Category: Qin, B.]]
[[Category: Qin, B.]]
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[[Category: transcription regulation]]
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[[Category: Transcription regulation]]
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[[Category: transferase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 17:53:17 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:39:45 2008''
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Revision as of 14:53, 3 May 2008

Template:STRUCTURE 1zoq

IRF3-CBP complex


Overview

Interferon regulatory factor (IRF) 3 plays a critical role in triggering the activation of interferon antiviral genes. The structure of IRF-3 in association with the CBP/p300 coactivator by in this issue of Structure illuminates the mechanism of IRF activation and the structural flexibilities inherent in CBP/p300.

About this Structure

1ZOQ is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

IRF-3 releases its inhibitions., Hiscott J, Lin R, Structure. 2005 Sep;13(9):1235-6. PMID:16154077 Page seeded by OCA on Sat May 3 17:53:17 2008

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