1ztl

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[[Image:1ztl.gif|left|200px]]
[[Image:1ztl.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1ztl |SIZE=350|CAPTION= <scene name='initialview01'>1ztl</scene>, resolution 2.60&Aring;
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The line below this paragraph, containing "STRUCTURE_1ztl", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=737:N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]-2-{6-OXO-5-[(QUINOLIN-8-YLMETHYL)-AMINO]-2-M-TOLYL-6H-PYRIMIDIN-1-YL}-ACETAMIDE'>737</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= F11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_1ztl| PDB=1ztl | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ztl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ztl OCA], [http://www.ebi.ac.uk/pdbsum/1ztl PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ztl RCSB]</span>
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}}
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'''Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide'''
'''Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide'''
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[[Category: Rynkiewicz, M.]]
[[Category: Rynkiewicz, M.]]
[[Category: Strickler, J E.]]
[[Category: Strickler, J E.]]
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[[Category: fxia]]
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[[Category: Fxia]]
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[[Category: inhibitor]]
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[[Category: Inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:03:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:41:30 2008''
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Revision as of 15:03, 3 May 2008

Image:1ztl.gif

Template:STRUCTURE 1ztl

Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide


Disease

Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]

About this Structure

1ZTL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA. Page seeded by OCA on Sat May 3 18:03:26 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

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