211d

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[[Image:211d.gif|left|200px]]
[[Image:211d.gif|left|200px]]
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{{Structure
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|PDB= 211d |SIZE=350|CAPTION= <scene name='initialview01'>211d</scene>, resolution 1.600&Aring;
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The line below this paragraph, containing "STRUCTURE_211d", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=PTN:PLATINUM+TRIAMINE+ION'>PTN</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>
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|DOMAIN=
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{{STRUCTURE_211d| PDB=211d | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=211d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=211d OCA], [http://www.ebi.ac.uk/pdbsum/211d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=211d RCSB]</span>
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'''THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE'''
'''THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE'''
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==About this Structure==
==About this Structure==
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211D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=211D OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=211D OCA].
==Reference==
==Reference==
Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7492550 7492550]
Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7492550 7492550]
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[[Category: Protein complex]]
 
[[Category: Arvantis, G M.]]
[[Category: Arvantis, G M.]]
[[Category: Berman, H M.]]
[[Category: Berman, H M.]]
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[[Category: Lessinger, L.]]
[[Category: Lessinger, L.]]
[[Category: Parkinson, G N.]]
[[Category: Parkinson, G N.]]
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[[Category: double helix]]
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[[Category: Double helix]]
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[[Category: modified]]
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[[Category: Modified]]
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[[Category: z-dna]]
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[[Category: Z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:18:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:44:15 2008''
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Revision as of 15:18, 3 May 2008

Template:STRUCTURE 211d

THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE


Overview

The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:7492550 Page seeded by OCA on Sat May 3 18:18:35 2008

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