243d
From Proteopedia
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[[Image:243d.gif|left|200px]] | [[Image:243d.gif|left|200px]] | ||
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| - | + | {{STRUCTURE_243d| PDB=243d | SCENE= }} | |
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'''STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2''' | '''STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=243D OCA]. | |
==Reference== | ==Reference== | ||
Structure of the DNA octanucleotide d(ACGTACGT)2., Wilcock DJ, Adams A, Cardin CJ, Wakelin LP, Acta Crystallogr D Biol Crystallogr. 1996 May 1;52(Pt 3):481-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299669 15299669] | Structure of the DNA octanucleotide d(ACGTACGT)2., Wilcock DJ, Adams A, Cardin CJ, Wakelin LP, Acta Crystallogr D Biol Crystallogr. 1996 May 1;52(Pt 3):481-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299669 15299669] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Adams, A.]] | [[Category: Adams, A.]] | ||
[[Category: Cardin, C J.]] | [[Category: Cardin, C J.]] | ||
[[Category: Wakelin, L P.G.]] | [[Category: Wakelin, L P.G.]] | ||
[[Category: Wilcock, D J.]] | [[Category: Wilcock, D J.]] | ||
| - | [[Category: | + | [[Category: A-dna]] |
| - | [[Category: | + | [[Category: Double helix]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:22:15 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 15:22, 3 May 2008
STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2
Overview
d(ACGTACGT), C(78)H(84)N(30)O(32)P(7).20H(2)O, M(r) (DNA) = 2170, tetragonal, P4(3)2(1)2 (No 96), a = 42.845 (1), b = 42.845(1), c = 24.804 (1) A, V = 45532.5 (2) A(3), z = 8,lambda(MoKalpha) = 0.71069 A, micro (MoKalpha) = 0.10 mm(-1), T = 295 K, R = 0.18 for 1994 unique reflections between 5.0 and 1.9 A resolution. The self-complementary octanucleotide d(ACGTACGT)(2) has been crystallized and its structure determined to a resolution of 1.9 A. The asymmetric unit consists of a single strand of octamer with 20 water molecules. It is only the second example of an octanucleotide having terminal A.T base pairs whose structure has been determined by X-ray crystallography. The sequence adopts the modified A-type conformation found for all octanucleotide duplexes studied to date with the helix bent by approximately 15 degrees and an average tilt angle of 0 degrees. Unusually the data collection was carried out using a 3 kW molybdenum sealed-tube source. The conformational details are discussed in comparison with other closely related sequences.
About this Structure
Full crystallographic information is available from OCA.
Reference
Structure of the DNA octanucleotide d(ACGTACGT)2., Wilcock DJ, Adams A, Cardin CJ, Wakelin LP, Acta Crystallogr D Biol Crystallogr. 1996 May 1;52(Pt 3):481-5. PMID:15299669 Page seeded by OCA on Sat May 3 18:22:15 2008
